Back in 1987, alarm about emissions of ozone layer-depleting chlorofluorocarbons (CFCs), hydrochlorofluorocarbons (HCFCs), and bromine gases led national governments worldwide to sign the Montreal Protocol on Substances that Deplete the Ozone Layer, a United Nations (UN) environmental agreement in which 197 countries and the European Union (EU) pledged to phase out production and use of CFCs, HCFCs and bromine gases. Though revised, more aggressive reduction targets for new refrigerant standards are being met, subsequent developments – rapid industrialization in large emerging market countries and the growing threats and costs of global warming – have complicated matters further.