An estimated 5.5 million Americans live with Alzheimer’s disease, a type of dementia that causes problems with memory, thinking and behavior. Although treatments can slow the worsening of symptoms, scientists are still working to better understand the neurodegenerative disease so that curative and preventative medicines can be developed. A new imaging system could help speed new drug development by offering a better way to monitor the brain changes indicative of Alzheimer’s in mouse models of the disease.